![]() ![]() In somatic cells, a mutation in a critical gene may lead to cancer. When a mutation is present in a germ cell, it is inherited to the next generation, and can cause a genetic disorder. Genotoxic events can be transient (repairable damage), or can lead to permanent changes (mutations) in the amount or structure of the genetic material in a cell. Genotoxicity describes the property of chemical or physical agents that are able to alter the genetic information. A main concern with NM exposure is their genotoxic potential. Due to constantly growing commercial applications and their presence in the majority of consumer products, NMs are being extensively investigated for their safety. ![]() They have already been in use for several decades, and are being utilized in almost every industrial sector. Nanomaterials (NMs) are materials with unique properties and size with at least one dimension between 1 and 100 nm, as defined by the European Commission (Regulation (EC) No. ![]()
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